In this game, the player controls a successful doctor who left his quiet hometown for Tokyo. There, he had a successful career at the central hospital, which made him forget his past life in the province. However, an inexplicable desire to return overcomes him, so he takes the next train to his hometown. He finds that many things have changed. Other people are living in his former house. His old lovers have a new life. Little children have turned into pretty young girls. Some people remember him and not everyone is happy about him leaving the town and moving to Tokyo. Now, the doctor wants to establish good relationship with the female inhabitants of the town... which for him, can only mean one thing.
Yuki Hotaru plays like a traditional Japanese adventure game, without exploration, puzzles, etc. Text boxes are displayed on top of 3D images or pre-rendered backgrounds. The seduction of the girls does not depend much on the hero's actions (even though the player is required to make decisions from time to time). Once in the seduction mode, the player is able to physically interact with the girl, by placing, clicking, and dragging the mouse button to imitate actual movements (for example, unbutton a shirt, caress a body part, etc.).